Abstract
PHARMACOLOGICALLY evoked selective degeneration of neurones with a specific function or functioning with known transmitter substances, has been reported only in the monoaminergic neurone systems1,2. We report here that selective degeneration of neurones with a highly specific function can be produced by chemical agents in the somatosensory system as well. Capsaicin given to newborn rats induces selective degeneration of a distinct population of primary sensory neurones involved in mediation of chemogenic pain.
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JANCSÓ, G., KIRALY, E. & JANCSÓ-GÁBOR, A. Pharmacologically induced selective degeneration of chemosensitive primary sensory neurones. Nature 270, 741–743 (1977). https://doi.org/10.1038/270741a0
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DOI: https://doi.org/10.1038/270741a0
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