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Comparative neutron small-angle scattering study of small spherical RNA viruses

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Abstract

Small-angle neutron scattering from solutions of small RNA viruses has been used to study protein–nucleic acid organisation. In the five viruses investigated the RNA is confined to a sphere of about 100 Å radius, with a central hole (with one possible exception). The interpenetration of RNA and protein varies with viruses and seems to be related to the nature of the forces stabilising the virus.

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Jacrot, B., Chauvin, C. & Witz, J. Comparative neutron small-angle scattering study of small spherical RNA viruses. Nature 266, 417–421 (1977). https://doi.org/10.1038/266417a0

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