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The structure of the protein disk of tobacco mosaic virus to 5 Å resolution

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Abstract

An electron density map of the TMV disk at 5 Å resolution has been obtained using isomorphous replacement and non-crystallographic symmetry. The polypeptide chain can be traced with little ambiguity. The axial contacts between protein subunits are unlike those in the virus, the disk being a more open structure apparently designed for rapid interaction with the RNA.

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Authors and Affiliations

  1. MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK

    J. N. Champness, A. C. Bloomer, G. Bricogne, P. J. G. Butler & A. Klug

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  1. J. N. Champness
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  2. A. C. Bloomer
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  3. G. Bricogne
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  4. P. J. G. Butler
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  5. A. Klug
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Champness, J., Bloomer, A., Bricogne, G. et al. The structure of the protein disk of tobacco mosaic virus to 5 Å resolution. Nature 259, 20–24 (1976). https://doi.org/10.1038/259020a0

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  • DOI: https://doi.org/10.1038/259020a0

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