Abstract
PROLACTIN, like other polypeptide and glycoprotein hormones from the pituitary gland, exerts its effects on target cells through interaction with receptors on the plasma membrane1–4. Unlike several other pituitary hormones, this does not occur through activation of adenyl cyclase5, and the mechanism of action of prolactin must therefore lie elsewhere.
Similar content being viewed by others
References
Turkington, R. W., Biochem. biophys. Res. Commun., 41, 1362–1367 (1970).
Birkinshaw, M., and Falconer, I. R., J. Endocr., 55, 323–334 (1972).
Shiu, R. P. C., and Friesen, H. G., J. biol. Chem., 249, 7902–7911 (1974).
Shiu, R. P. C., and Friesen, H. G., Biochem. J., 140, 301–311 (1974).
Turkington, R. W., in Lactogenic Hormones (edit. by Wolstenholme, G. E. W., and Knight, J.), 111–127 (Churchill–Livingstone, Edinburgh and London, 1972).
Ensor, D. M., and Ball, J. N., Fedn Proc., 31, 1615–1623 (1972).
Hart, I. C., J. Endocr., 57, 179 (1973).
Skou, J. C., Physiol. Rev., 45, 596–617 (1965).
Cotlove, E., Tranthan, H. V., and Bowman, R. L., J. Lab. clin. Med., 31, 461–468 (1958).
Kinura, T. J., Japan Obstet. Gynec. Soc., 21, 301–308 (1969).
Cowie, A. T., J. Endocr., 44, 437–450 (1969).
Linzell, J. M., and Peaker, J. L., Physiol. Rev., 51, 564–597 (1971).
Kroeger, H., in Endocrine Genetics (edit. by Spickett, S. G.), Endocr. Soc. Symp., 15, 55–66 (Cambridge University Press, Cambridge, 1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
FALCONER, I., ROWE, J. Possible mechanism for action of prolactin on mammary cell sodium transport. Nature 256, 327–328 (1975). https://doi.org/10.1038/256327a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/256327a0
- Springer Nature Limited
This article is cited by
-
Effect of prolactin on human red cell sodium transport
Experientia (1980)
-
Electrophysiological study of coupling between cultured cells of the mouse mammary gland in five distinct physiological states
The Journal of Membrane Biology (1976)