Skip to main content
SpringerLink
Log in

Y chromosome effect on adult testis size

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

DURING the development of mammals with X and Y chromosomes the Y chromosome brings about the differentiation of the gonad primordia into testes1. But apart from carrying the genetic determinants of maleness, little is known about its genetic constitution. In man, the gene for hairy tips to the ears shows Y linkage in at least some pedigrees2. In mice there is evidence for a Y-linked histocompatibility locus3,4, and for effects of the Y chromosome on the frequency of spermatozoa with abnormal heads5. Here we show that the size of the testes of adult mice is affected by factors on the Y chromosome.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Welshons, W. J., and Russell, L. B., Proc. natn. Acad. Sci., U.S.A., 45, 560–566 (1959).

    Article  ADS  CAS  Google Scholar 

  2. Dronamraju, K. R., Adv. Genet., 13, 225–310 (1965).

    Google Scholar 

  3. Eichwald, E. J., and Silmser, C. R., Transpln Bull., 5, 148–149 (1955).

    Google Scholar 

  4. Polácková, M., and Vojtísková, M., Folia biol., Praha, 19, 281–288 (1973).

    Google Scholar 

  5. Krzanowska, H., Genet. Res. 13, 17–24 (1969): Proc. int. Symp. Genet. Spermatozoon, 370–386, (edit. Beatty, R. A., and Gluecksohn-Waelsch, S., University of Edinburgh, 1972).

    Google Scholar 

  6. Shire, J. G. M., Excerpta Medica Int. Congr. Ser., 184, 328–332 (1969).

    Google Scholar 

  7. Shire, J. G. M., and Bartke, A., J. Endocr., 55, 163–171 (1972).

    Article  CAS  Google Scholar 

  8. Hayward, P., Thesis, University of Cambridge, (1973).

  9. Bartke, A., and Krzanowska, H., J. Hered., 63, 172–174 (1972).

    Article  CAS  Google Scholar 

  10. Bartke, A., and Shire, J. G. M., J. Endocr., 55, 173–184 (1972).

    Article  CAS  Google Scholar 

  11. Chai, C. K., Anat. Rec., 126, 269–282 (1956).

    Article  CAS  Google Scholar 

  12. Bartke, A., J. Endocr., 60, 145–148 (1974).

    Article  CAS  Google Scholar 

  13. Iványi, P., Gregorová, S., and Micková, M., Folia biol., Praha, 18, 81–97 (1972).

    Google Scholar 

  14. Mittwoch, U., Genetics of Sex Differentiation (Academic Press, London, 1973).

    Book  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Applied Research of Cambridge, Ltd, 5 Jesus Lane, Cambridge, CB5 8BA, UK

    PETER HAYWARD

  2. Institute of Genetics, University of Glasgow, Glasgow, G11 5JS, UK

    JOHN G. M. SHIRE

Authors
  1. PETER HAYWARD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. JOHN G. M. SHIRE
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Requests for reprints.

Rights and permissions

Reprints and permissions

About this article

Cite this article

HAYWARD, P., SHIRE, J. Y chromosome effect on adult testis size. Nature 250, 499–500 (1974). https://doi.org/10.1038/250499a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/250499a0

  • Springer Nature Limited

This article is cited by

Search

Navigation