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Properties of afferent nerve impulses originating from a neuroma

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Abstract

Damaged nerves attempt to regenerate. The nerve membrane changes its properties, becomes spontaneously active and may be the source of pain. These impulse generators have unusual properties. They become silent after high frequency activity. This silence may partially explain the effect of counterstimulation as a pain therapy.

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Authors and Affiliations

  1. Department of Anatomy, University College, London, WC1E 6BT

    Patrick D. Wall

  2. Department of Zoology, Hebrew University, Jerusalem, Israel

    Patrick D. Wall & Michael Gutnick

Authors
  1. Patrick D. Wall
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  2. Michael Gutnick
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Wall, P., Gutnick, M. Properties of afferent nerve impulses originating from a neuroma. Nature 248, 740–743 (1974). https://doi.org/10.1038/248740a0

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  • DOI: https://doi.org/10.1038/248740a0

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