Skip to main content
SpringerLink
Log in

Further observations on the structure of the lipid-containing bacteriophage PM2

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

RECENT work on the proteins of bacteriophage PM2 have led us to a model for the structure of this virus, proposed in this communication. Experimental results have enabled us to assign each of the four proteins1 to morphological structures of the virus revealed by electron microscopic and structural studies. Packing considerations indicate that protein II must form the outer protein shell2. Both proteins I and II are on the outside of the phage particle as demonstrated by labelling with radioactive iodine after lactoperoxidase treatment3 by the method of Phillips and Morrison4,5.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Datta, A., Camerini-Otero, R. D., Braunstein, S. N., and Franklin, R. M., Virology, 45, 232 (1971).

    Article  CAS  Google Scholar 

  2. Harrison, S. C., Caspar, D. L. D., Camerini-Otero, R. D., and Franklin, R. M., Nature new Biol., 229, 197 (1971).

    Article  CAS  Google Scholar 

  3. Braunstein, S. N., thesis, New York Univ. School of Medicine (1972).

  4. Phillips, D. R., and Morrison, M., Biochem. biophys. Res. Commun., 40, 284 (1970).

    Article  CAS  Google Scholar 

  5. Phillips, D. R., and Morrison, M., Biochemistry, N.Y., 10, 1766 (1971).

    Article  CAS  Google Scholar 

  6. Berg, H. C., Biochim. biophys. Acta, 183, 65 (1969).

    Article  CAS  Google Scholar 

  7. Camerini-Otero, R. D., Datta, A., and Franklin, R. M., Virology, 49, 522 (1972).

    Article  CAS  Google Scholar 

  8. Braunstein, S. N., and Franklin, R. M., Virology, 43, 685 (1971).

    Article  CAS  Google Scholar 

  9. Camerini-Otero, R. D., and Franklin, R. M., Virology, 49, 385 (1972).

    Article  CAS  Google Scholar 

  10. Maddy, A. H., Biochim. biophys. Acta, 88, 390 (1964).

    CAS  PubMed  Google Scholar 

  11. Bretscher, M. S., J. molec. Biol., 71, 523 (1972).

    Article  CAS  Google Scholar 

  12. Tsukagoshi, N., and Franklin, R. M., Virology (in the press).

Download references

Author information

Authors and Affiliations

  1. Department of Structure Biology, Biozentrum, University of Basel, Basel, Switzerland

    ROLF SCHAEFER, ROSMARIE HINNEN & RICHARD M. FRANKLIN

Authors
  1. ROLF SCHAEFER
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. ROSMARIE HINNEN
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. RICHARD M. FRANKLIN
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

SCHAEFER, R., HINNEN, R. & FRANKLIN, R. Further observations on the structure of the lipid-containing bacteriophage PM2. Nature 248, 681–682 (1974). https://doi.org/10.1038/248681a0

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1038/248681a0

  • Springer Nature Limited

This article is cited by

Search

Navigation