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Presence of EBV Antibodies in Sera from Wild Chimpanzees

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Abstract

THE marked geographical distribution of Burkitt's lymphoma in Africa has suggested that the aetiological agent is infectious and arthropod-borne1,2. A herpes-like virus, first described by Epstein et al.3, has been associated consistently with lymphoid cells cultured from cases of Burkitt's lymphoma4. Furthermore, immunofluorescent tests, using Burkitt lymphoma cells, have demonstrated antibodies against this Epstein-Barr virus (EBV) in all sera from patients with Burkitt's lymphoma and in sera from many healthy African controls living in the endemic regions5–6. These observations indicate that EBV infection is widespread, and suggest that the virus in some individuals might be involved in the development of Burkitt's tumour.

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Authors and Affiliations

  1. Department of Medicine, University of California, San Francisco, California

    JAY A. LEVY

  2. Blood Research Laboratory, New England Medical Center Hospitals, Boston, Massachusetts

    STUART B. LEVY

  3. Sloan-Kettering Memorial Hospital, New York

    YASHAR HIRSHAUT

  4. East African Viral Institute, Entebbe

    GEORGE KAFUKO

  5. New York Blood Center, New York

    ALFRED PRINCE

Authors
  1. JAY A. LEVY
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  2. STUART B. LEVY
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  3. YASHAR HIRSHAUT
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  4. GEORGE KAFUKO
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  5. ALFRED PRINCE
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LEVY, J., LEVY, S., HIRSHAUT, Y. et al. Presence of EBV Antibodies in Sera from Wild Chimpanzees. Nature 233, 559–560 (1971). https://doi.org/10.1038/233559a0

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  • DOI: https://doi.org/10.1038/233559a0

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