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Circadian Periodicity of Blood Amino-acids in Normal and Adrenalectomized Mice

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Abstract

THE total amino-acid concentration of healthy young men varies considerably with the time of day1,2. The periodicity of eighteen amino-acids in healthy adult males has been reported and the factors affecting their periodicity discussed3. Investigation of the regulation of plasma amino-acid rhythm through the corticoid rhythm was thought to be imperative4. We report a circadian periodicity for blood amino-acids in mice as well as the effect of adrenalectomy on the observed rhythmicity.

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Author notes

  1. RALPH D. FEIGIN

    Present address: St Louis Children's Hospital, 500 South Kingshighway, St Louis, Missouri

Authors and Affiliations

  1. Department of Pediatrics, Washington University School of Medicine and the US Army Medical Unit, Fort Detrick, Maryland

    RALPH D. FEIGIN, HARRY G. DANGERFIELD & WILLIAM R. BEISEL

Authors
  1. RALPH D. FEIGIN
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  2. HARRY G. DANGERFIELD
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  3. WILLIAM R. BEISEL
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FEIGIN, R., DANGERFIELD, H. & BEISEL, W. Circadian Periodicity of Blood Amino-acids in Normal and Adrenalectomized Mice. Nature 221, 94–95 (1969). https://doi.org/10.1038/221094a0

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  • DOI: https://doi.org/10.1038/221094a0

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