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Metabolism of Testosterone and Action of Metabolites on Prostate Glands grown in Organ Culture

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Abstract

TESTOSTERONE metabolites are found in the prostate gland in vivo1,2 and preliminary experiments, briefly reported3, indicate that prostatic tissue grown in vitro metabolizes the hormone. The action of testosterone could be caused directly by the hormone, or indirectly through its transformation into metabolites, for example, through tran-hydrogenation4, or to metabolites themselves5.

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Authors and Affiliations

  1. Unité de Recherches sur le Métabolisme Moléculaire et la Physio-Pathologie des Stéroides, Faculté de Médecine de Paris, and Strangeways Research Laboratory, Cambridge

    E. E. BAULIEU, ILSE LASNITZKI & P. ROBEL

Authors
  1. E. E. BAULIEU
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  2. ILSE LASNITZKI
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  3. P. ROBEL
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BAULIEU, E., LASNITZKI, I. & ROBEL, P. Metabolism of Testosterone and Action of Metabolites on Prostate Glands grown in Organ Culture. Nature 219, 1155–1156 (1968). https://doi.org/10.1038/2191155a0

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  • DOI: https://doi.org/10.1038/2191155a0

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