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Erythropoietin and the Development of Erythrocytes: Effect of Erythropoietin in vitro which simulates that of a Massive Dose in vivo

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Abstract

During the differentiation of erythrocytes some cells develop which contain a high concentration of haemoglobin and no cytoplasmic basophilia. Erythropoietin has the effect of increasing the proportion of these cells in preparations of marrow. Two of the communications which follow discuss the effect on these cells of erythropoietin and of ageing and haemorrhage. The third communication describes a factor in the serum of a polycythaemic calf which enhances the activity of erythropoietin.

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Author notes

  1. DIAN TEIGLER

    Present address: Department of Botany, University of Texas, Austin, Texas

Authors and Affiliations

  1. Space Sciences Laboratory, University of California, Berkeley

    HENRY BORSOOK, KAREN RATNER, BRENDA TATTRIE & DIAN TEIGLER

  2. Paterson Laboratories, Christie Hospital and Holt Radium Institute, Manchester

    L. G. LAJTHA

Authors
  1. HENRY BORSOOK
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  2. KAREN RATNER
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  3. BRENDA TATTRIE
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  4. DIAN TEIGLER
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  5. L. G. LAJTHA
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BORSOOK, H., RATNER, K., TATTRIE, B. et al. Erythropoietin and the Development of Erythrocytes: Effect of Erythropoietin in vitro which simulates that of a Massive Dose in vivo. Nature 217, 1024–1026 (1968). https://doi.org/10.1038/2171024a0

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  • DOI: https://doi.org/10.1038/2171024a0

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