Skip to main content

Advertisement

SpringerLink
Log in

Prostaglandins: Their Disappearance from and Release into the Circulation

  • Article
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

Prostaglandins are released into the splenic venous blood when the spleen contracts. Whatever the significance of this release, the liver and lungs provide an efficient protective mechanism to remove almost all the prostaglandin before it reaches the arterial circulation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Bergström, S., Rec. Prog. Hormone Res., 22, 163 (1966).

    Google Scholar 

  2. Ramwell, P. W., Shaw, J. E., Douglas, W. W., and Poisner, A. M., Nature, 210, 273 (1966).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Davies, R. B., Horton, E. W., and Witherington, P. G., J. Physiol., 188, 38P (1967).

    CAS  PubMed  Google Scholar 

  4. Bergström, S., Duner, H., v. Euler, U. S., Pernow, B., and Sjövall, J., Acta Physiol. Scand., 45, 145 (1959).

    Article  PubMed  Google Scholar 

  5. Horton, E. W., and Main, I. H. M., Brit. J. Pharmacol. Chemother., 21, 182 (1963).

    Article  CAS  Google Scholar 

  6. Horton, E. W., and Thompson, C. J., Brit. J. Pharmacol. Chemother., 22, 183 (1964).

    Article  CAS  Google Scholar 

  7. Vane, J. R., Brit. J. Pharmacol. Chemother., 23, 360 (1964).

    Article  CAS  Google Scholar 

  8. Gaddum, J. H., Brit. J. Pharmacol. Chemother., 8, 321 (1953).

    Article  CAS  Google Scholar 

  9. Paton, W. D. M., J. Physiol., 137, 35P (1957).

    CAS  PubMed  Google Scholar 

  10. Vane, J. R., Brit. J. Pharmacol. Chemother., 12, 344 (1957).

    Article  CAS  Google Scholar 

  11. Regoli, D., and Vane, J. R., Brit. J. Pharmacol. Chemother., 23, 351 (1964).

    Article  CAS  Google Scholar 

  12. Mann, M., and West, G. B., Brit. J. Pharmacol. Chemother., 5, 173 (1950).

    Article  CAS  Google Scholar 

  13. Regoli, D., and Vane, J. R., J. Physiol., 183, 513 (1966).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Ferreira, S. H., and Vane, J. R., Brit. J. Pharmacol. Chemother., 30, 417 (1967).

    Article  CAS  Google Scholar 

  15. Ambache, N., J. Physiol., 148, 255 (1959).

    Article  Google Scholar 

  16. Ambache, N., Brummer, H. C., Whiting, J. G., and Whiting, R., J. Physiol., 185, 77 (1966).

    Google Scholar 

  17. Horton, E. W., Main, I. H. M., and Thompson, C. J., J. Physiol., 180, 514 (1965).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  18. Carlson, L. A., and Orö, L., Acta Physiol. Scand., 67, 89 (1966).

    Article  CAS  PubMed  Google Scholar 

  19. Samuelsson, B., J. Biol. Chem., 239, 4091 (1964).

    CAS  PubMed  Google Scholar 

  20. Hansson, E., and Samuelsson, B., Biochim. Biophys. Acta, 106, 379 (1965).

    Article  CAS  PubMed  Google Scholar 

  21. Anggård, E., and Samuelsson, B., J. Biol. Chem., 239, 4097 (1964).

    Google Scholar 

  22. Anggård, E., and Samuelsson, B., Ark. Kemi, 25, 293 (1966).

    Google Scholar 

Download references

Author information

Author notes

  1. S. H. FERREIRA

    Present address: Department of Pharmacology, Faculdade de Medicina de Ribeirão Preto, São Paulo, Brazil

Authors and Affiliations

  1. Department of Pharmacology, Institute of Basic Medical Sciences, Royal College of Surgeons of England, London

    S. H. FERREIRA & J. R. VANE

Authors
  1. S. H. FERREIRA
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. R. VANE
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

FERREIRA, S., VANE, J. Prostaglandins: Their Disappearance from and Release into the Circulation. Nature 216, 868–873 (1967). https://doi.org/10.1038/216868a0

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1038/216868a0

  • Springer Nature Limited

This article is cited by

Search

Navigation