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In vitro Studies of Aggregation of Non-mammalian Thrombocytes

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Abstract

NON-MAMMALIAN thrombocytes are nucleated cells which have been shown to have a haemostatic function paralleling that of mammalian platelets. Thrombocytes are active in the promotion of clots1 and clot retraction2, and respond in vivo to damage of the vessel wall by aggregating to form a plug3. Platelets have been shown to aggregate in the presence of adenosine diphosphate (ADP)4 and therefore it seemed pertinent to study aggregation of thrombocytes with compounds and techniques used in the study of platelets. Although the term thrombocyte is frequently used as a synonym for the mammalian platelet, in this paper it is used solely to describe the nucleated, non-mammalian haemostatic cell.

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References

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Authors and Affiliations

  1. Department of Biology, Boston University, Boston, Massachusetts

    FRANK A. BELAMARICH, MARGARET H. FUSARI, DAVID SHEPRO & MARJA KIEN

  2. The Marine Biological Laboratory, Woods Hole, Massachusetts

    FRANK A. BELAMARICH, MARGARET H. FUSARI, DAVID SHEPRO & MARJA KIEN

Authors
  1. FRANK A. BELAMARICH
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  2. MARGARET H. FUSARI
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  3. DAVID SHEPRO
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  4. MARJA KIEN
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BELAMARICH, F., FUSARI, M., SHEPRO, D. et al. In vitro Studies of Aggregation of Non-mammalian Thrombocytes. Nature 212, 1579–1580 (1966). https://doi.org/10.1038/2121579a0

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