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Determination of Nicotine and its Metabolite, Cotinine, in Urine by Gas Chromatography

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Abstract

A VARIETY of methods have been described for the identification and determination of nicotine in biological fluids1–4; however, they lack sensitivity, specificity and are tedious for routine analysis.

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BECKETT, A., TRIGGS, E. Determination of Nicotine and its Metabolite, Cotinine, in Urine by Gas Chromatography. Nature 211, 1415–1417 (1966). https://doi.org/10.1038/2111415a0

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