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Chemical Transmission at the Insect Excitatory Neuromuscular Synapse

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Abstract

GLUTAMIC acid mimics the transmitter at the crustacean excitatory neuromuscular synapse1 and has been tentatively identified with the chemical mediator at the insect peripheral excitatory synapse2,3. Similarities in the pharmacology of insect and crustacean excitatory neuromuscular synapses are, perhaps, to be expected since the pharmacological properties of their peripheral inhibitory synapses are remarkably similar2,4. In an effort to determine the site of action of glutamic acid on the insect neuromuscular system we have examined the effects of this substance on the electrical and mechanical properties of a locust neuromuscular preparation.

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References

  1. Takeuchi, A., and Takeuchi, N., J. Physiol., 170, 296 (1964).

    Article  CAS  Google Scholar 

  2. Usherwood, P. N. R., and Grundfest, H., J. Neurophysiol., 28, 497 (1965).

    Article  CAS  Google Scholar 

  3. Kerkut, G. A., Leake, L. D., Cowan, S., Shapira, A., and Walker, R. J., Comp. Biochem. Physiol., 15, 485 (1965).

    Article  CAS  Google Scholar 

  4. Usherwood, P. N. R., and Grundfest, H., Science, 143, 817 (1964).

    Article  ADS  CAS  Google Scholar 

  5. Usherwood, P. N. R., Nature, 191, 814 (1961).

    Article  ADS  CAS  Google Scholar 

  6. Usherwood, P. N. R., J. Physiol., 169, 149 (1963).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Zoology, University of Glasgow,

    P. N. R. USHERWOOD & P. MACHILI

Authors
  1. P. N. R. USHERWOOD
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  2. P. MACHILI
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USHERWOOD, P., MACHILI, P. Chemical Transmission at the Insect Excitatory Neuromuscular Synapse. Nature 210, 634–636 (1966). https://doi.org/10.1038/210634a0

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