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Erythropoietic Stimulation in the Hypertransfused Guinea-Pig following Injections of Human Urinary Erythropoietin

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Abstract

CONSIDERABLE evidence has accumulated in recent years that supports the concept of a humoral component as part of the mechanism for control of erythropoiesis. The humoral agent has been termed erythropoietin or erythropoietic stimulating factor, and has been obtained from plasma and urine of various anæmic animals and from urine of patients with various hæmatological disorders. Erythropoietin does not appear to be species specific; thus, human, rabbit and sheep erythropoietin stimulate erythropoiesis in the mouse, rat and rabbit.

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References

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Authors and Affiliations

  1. Donner Laboratory, University of California Lawrence Radiation Laboratory, Berkeley

    JOSEPH F. GARCIA & JOHN C. SCHOOLEY

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  1. JOSEPH F. GARCIA
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  2. JOHN C. SCHOOLEY
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GARCIA, J., SCHOOLEY, J. Erythropoietic Stimulation in the Hypertransfused Guinea-Pig following Injections of Human Urinary Erythropoietin. Nature 196, 279–280 (1962). https://doi.org/10.1038/196279a0

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