Abstract
IN seeking simple physiological methods for blocking followed by synchronization of cell division, materials were sought which, applied for prolonged periods, permitted synthesis of ribonucleic acid (RNA) and protein but inhibited cells immediately prior to DNA replication. During this I used excess (2 mM) thymidine as a blocking-synchronizing agent.
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References
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XEROS, N. Deoxyriboside Control and Synchronization of Mitosis. Nature 194, 682–683 (1962). https://doi.org/10.1038/194682a0
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DOI: https://doi.org/10.1038/194682a0
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