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Concentration and Partial Purification of Poliovirus by means of Zinc Hydroxide and Ion-exchanging Resin

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Abstract

Newton and Bevis1 concentrated some animal viruses by adding zinc hydroxide to the virus suspension and afterwards dissolving the gel in saturated ethylenediamine tetraacetic acid solution in order to recover the virus. Attempts made in our laboratory to concentrate poliovirus by this method yielded unsatisfactory results.

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References

  1. Newton, N., and Bevis, R., Virology, 8, 344 (1959).

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  2. Grossowicz, N., Mercado, A., and Goldblum, N., Proc. Soc. Exp. Biol. and Med., 103, 872 (1960).

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  3. Le Bouvier, G., Brit. J. Exp. Pathol., 40, 452 (1959).

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Authors and Affiliations

  1. Department of Poliomyelitis, Dr. I. Cantacuzino Institute, Bucarest

    FLORIAN HORODNICEANU, DINA SERGIESCU, RICHARD KLEIN & ANDREI AUBERT-COMBIESCU

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  1. FLORIAN HORODNICEANU
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  2. DINA SERGIESCU
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  3. RICHARD KLEIN
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  4. ANDREI AUBERT-COMBIESCU
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HORODNICEANU, F., SERGIESCU, D., KLEIN, R. et al. Concentration and Partial Purification of Poliovirus by means of Zinc Hydroxide and Ion-exchanging Resin. Nature 193, 600–601 (1962). https://doi.org/10.1038/193600b0

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  • DOI: https://doi.org/10.1038/193600b0

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