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Release of Noradrenaline from the Spleen of the Cat by Acetylcholine

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An Erratum to this article was published on 10 February 1962

Abstract

ACETYLCHOLINE contracts the spleen of the dog1 and cat2. In these species the effect of acetylcholine in contracting the spleen is not blocked by atropine, but is blocked by dibenzyline and reduced by prior treatment of the animal with reserpine; thus it appears that the action of acetylcholine may be mediated by releasing noradrenaline from its stores in the spleen, which afterwards causes a contraction. The work reported here provides further evidence that acetylcholine liberates noradrenaline from the cat spleen.

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References

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Author notes

  1. HELEN BOYD

    Present address: Department of Zoology, University of Melbourne, Victoria, Australia

Authors and Affiliations

  1. Department of Pharmacology, University of Sydney, New South Wales

    K. W. BRANDON & HELEN BOYD

Authors
  1. K. W. BRANDON
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  2. HELEN BOYD
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BRANDON, K., BOYD, H. Release of Noradrenaline from the Spleen of the Cat by Acetylcholine. Nature 192, 880–881 (1961). https://doi.org/10.1038/192880a0

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