Abstract
THE rate of incorporation of acetate labelled with carbon-14 into the liver phospholipids of rats treated with growth hormone is reduced to about 50 per cent of that found in normal animals1. On the other hand the rate of incorporation of orthophosphate labelled with phosphorus-32 in similarly treated animals is increased by about 30 per cent2. It thus appeared that growth hormone might affect the rates of synthesis of the fatty acid skeleton and the phosphoryl-base moiety separately.
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References
Greenbaum, A. L., and Glascock, R. F., Biochem. J., 67, 360 (1957).
Greenbaum, A. L., Graymore, C. N., and Slater, J., Endocrinol., 15, 235 (1957).
Stadie, W. C., and Riggs, B. C., J. Biol. Chem., 154, 687 (1944).
Greenbaum, A. L., and McLean, P., Biochem. J., 54, 407 (1953).
Kennedy, E. P., J. Biol. Chem., 201, 399 (1953).
Kline, D., McPherson, C., Pritchard, E. T., and Rossiter, R. J., J. Biol. Chem., 222, 219 (1956).
Riley, R. F., J. Amer. Chem. Soc., 66, 512 (1944).
Kennedy, E. P., and Weiss, S. B., J. Biol. Chem., 222, 193 (1956).
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LEAL, R., GREENBAUM, A. Incorporation of Phosphoryl-choline labelled with Phosphorus-32 into the Liver Phospholipids of Rats treated with Growth Hormone. Nature 190, 548–549 (1961). https://doi.org/10.1038/190548a0
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DOI: https://doi.org/10.1038/190548a0
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