Abstract
SYNTHETIC peptides prepared by Hofmann and associates1 containing 8, 10 or 13 amino-acids identical in sequence with the N-terminal portion of corticotropin were tested for adipokinetic activity because corticotropin was known to have this activity2–4. The tridecapeptides caused the release of free fatty acids by adipose tissue; the decapeptides were also active but less potent, but the octapeptide had no effect in the amounts tested.
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References
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Waller, J.-P., and Dixon, H. B. F., Biochem. J., 75, 320 (1960).
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RABEN, M., LANDOLT, R., SMITH, F. et al. Adipokinetic Activity of Synthetic Peptides Related to Corticotropin. Nature 189, 681–682 (1961). https://doi.org/10.1038/189681a0
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DOI: https://doi.org/10.1038/189681a0
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