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Evidence for the Existence of Two Corticotrophin-releasing Factors, α and β

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Abstract

WE wish to report here the presence of two distinct peptides with corticotrophin-releasing factor activity in hog posterior pituitary extracts. All the separation methods as well as the bioassays for corticotrophin-releasing factor, adrenocorticotrophic hormone, vasopressin and melanocyte stimulating hormone have been described previously1–6.

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References

  1. Guillemin, R., Hearn, W. H., Cheek, W. R., and Housholder, D. E., Endocrinol., 60, 488 (1957).

    Article  CAS  Google Scholar 

  2. Schally, A. V., Saffran, M., and Zimmerman, B., Biochem. J., 70, 97 (1958).

    Article  CAS  Google Scholar 

  3. Schally, A. V., and Guillemin, R., Tex. Rep. Biol. Med., 18, 133 (1960).

    CAS  PubMed  Google Scholar 

  4. Guillemin, R., and Schally, A. V., Endocrinol., 65, 555 (1959).

    Article  CAS  Google Scholar 

  5. Schally, A. V., Andersen, R. N., Long, J. M., and Guillemin, R., Proc. Soc. Exp. Biol. Med., 104, 290 (1960).

    Article  CAS  Google Scholar 

  6. Schally, A. V., and Guillemin, R., Proc. Soc. Exp. Biol. Med., 100, 138 (1959).

    Article  CAS  Google Scholar 

  7. Harris, J. I., Biochem. J., 71, 451 (1959).

    Article  CAS  Google Scholar 

  8. Gros, C., and Privat de Garilhe, M., C.R. Acad. Sci., Paris, 249, 2234 (1959).

    CAS  Google Scholar 

  9. Royce, P. C., and Sayers, G., Proc. Soc. Exp. Biol. Med., 103, 447 (1960).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Physiology, Baylor University College of Medicine, Houston, Texas

    A. V. SCHALLY, R. N. ANDERSEN, H. S. LIPSCOMB, J. M. LONG & ROGER GUILLEMIN

  2. Laboratoire de Morphologie expérimentale et Endocrinologie, College de France, Paris

    A. V. SCHALLY, R. N. ANDERSEN, H. S. LIPSCOMB, J. M. LONG & ROGER GUILLEMIN

Authors
  1. A. V. SCHALLY
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  2. R. N. ANDERSEN
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  3. H. S. LIPSCOMB
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  4. J. M. LONG
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  5. ROGER GUILLEMIN
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SCHALLY, A., ANDERSEN, R., LIPSCOMB, H. et al. Evidence for the Existence of Two Corticotrophin-releasing Factors, α and β. Nature 188, 1192–1193 (1960). https://doi.org/10.1038/1881192a0

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