Abstract
IT has been pointed out that central inhibition is connected with an increase of acetylcholine content in brain tissue. On the other hand it has also been shown that some central depressants reduce the oxygen uptake of normal respiring brain tissue in vitro 1 or in brain slices which were stimulated electrically2.
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References
Jowett, M., J. Physiol., 92, 322 (1938).
McIlwain, H., Biochem. J., 53, 403 (1953).
Zelený, A., Lindaur, V., and Kozák, J., Arch. Exp. Path. Pharmakol., 231, 593 (1957).
Zelený, A., and Kozák, J., International Symposium: Pharmacology of the Nervous Excitability, Liblice, C. S.R. (1959).
McIlwain, H., Brit. J. Pharmacol., 6, 531 (1951).
Abood, L. G., and Bomanchek, L., Ann. N.Y. Acad. Sci., 66, 812 (1957).
Decsi, L., Arzneim.-Forsch., 8, 348, 352 (1958).
Decsi, L., Acta Physiol. Hung., 10, 387 (1956).
Vlk, J., Cs. fysiol., 7, 576 (1958).
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KOZÁK, J., ZELENÝ, A. & LANG, N. Effect of Chlorpromazine on Tissue Metabolism in vitro . Nature 185, 107–108 (1960). https://doi.org/10.1038/185107a0
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DOI: https://doi.org/10.1038/185107a0
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