Skip to main content
SpringerLink
Log in

Neuromuscular Blocking Action of some Antibiotics

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

CURARE-LIKE effects due to streptomycin and neomycin have been reported1–3. These two antibiotics have been shown to be capable of exerting a curariform block of the neuromuscular transmission2–4. One of us (G.B.) observed that some patients under heavy antibiotic treatment were more sensitive to the muscular relaxant action of d-tubocurarine. We have therefore begun to study the influence exerted by the most widely used antibiotics on the sensitivity of rabbits to the paralysing activity of curarizing drugs.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Loder, R. E., and Walker, G. F., Lancet, i, 812 (1959).

  2. Pittinger, G. B., and Long, J. P., Antibiotics and Chemotherapy, 8, 198 (1958).

    CAS  PubMed  Google Scholar 

  3. Foldes, F. F., Anæsthesia, 13, 191 (1958).

    Article  Google Scholar 

  4. Brazil, O. V., and Corrado, A. P., J. Pharmacol., 120, 452 (1957).

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Pharmacology and Institute of Surgical Pathology, University of Cagliari, Italy

    G. BEZZI & G. L. GESSA

Authors
  1. G. BEZZI
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. L. GESSA
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

BEZZI, G., GESSA, G. Neuromuscular Blocking Action of some Antibiotics. Nature 184, 905–906 (1959). https://doi.org/10.1038/184905a0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/184905a0

  • Springer Nature Limited

This article is cited by

Search

Navigation