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Co-existence of the Embryonic (Third Normal) Hæmoglobin Fraction with Erythroblastosis in the Blood of Two Full-term New-born Babies with Multiple Malformations

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Abstract

IN previous communications1,2 the existence of a third normal, embryonic hæmoglobin was reported to be present in the blood of fœtuses up to five months of intra-uterine life. The hæmolysates of the blood of these fœtuses were characterized by their electrophoretic mobility on filter paper in a buffer solution of p H 8.6, which was slower than that shown by the hæmolysates obtained from the cord blood of full-term new-borns. The paper electrophoresis method did not permit us, however, to separate the different hæmoglobin fractions present either in the fœtal or in the embryonic blood.

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References

  1. Halbrecht, I., and Klibanaski, Ch., Nature, 178, 794 (1956).

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  2. Halbrecht, I., Klibanaski, Ch., Brzoza, H., and Lahav, M., Amer. J. Clin. Path., 29, 340 (1958).

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  3. Huisman, T. H. J., and Prins, H. K., Clin. Chim. Acta, 2, 307 (1957).

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HALBRECHT, I., KLIBANSKI, C. & ILAN, F. Co-existence of the Embryonic (Third Normal) Hæmoglobin Fraction with Erythroblastosis in the Blood of Two Full-term New-born Babies with Multiple Malformations. Nature 183, 327–328 (1959). https://doi.org/10.1038/183327a0

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