Abstract
WE have already reported1 that in a phosphate-deficient medium the amount of ribonucleic acid in E. coli decreased remarkably, while there was an appreciable increase of deoxyribonucleic acid, protein and viable cell numbers. At the same time we also studied activities of some enzymes presumed to be related to the degradation of ribonucleic acid, for example, ribonuclease phosphodiesterase and phosphomonoesterase, and found a marked increase in that of phosphomonoesterase. This communication is concerned with this formation of phosphomonoesterase in E. coli.
Similar content being viewed by others
References
Horiuchi, T., Horiuchi, S., and Mizuno, D., Biochim. Biophys. Acta, 31, 570 (1959).
Bessey, O. A., Lowry, O. H., and Borock, M. J., J. Biol. Chem., 164, 321 (1946).
Novick, A., and Weiner, M., Proc. U.S. Nat. Acad. Sci., 43, 553 (1957).
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
Umbarger, E., and Brown, B., J. Biol. Chem., 233, 415 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HORIUCHI, T., HORIUCHI, S. & MIZUNO, D. A Possible Negative Feedback Phenomenon controlling Formation of Alkaline Phosphomonoesterase in Escherichia coli . Nature 183, 1529–1530 (1959). https://doi.org/10.1038/1831529b0
Issue Date:
DOI: https://doi.org/10.1038/1831529b0
- Springer Nature Limited
This article is cited by
-
Boosting toxic protein biosynthesis: transient in vivo inactivation of engineered bacterial alkaline phosphatase
Microbial Cell Factories (2020)
-
Synergistic activation of Toll-like receptor 8 by two RNA degradation products
Nature Structural & Molecular Biology (2015)
-
Potentialities and prospects for the use of alkaline phosphatases for determining metal ions
Journal of Analytical Chemistry (2005)
-
Nutritional control of copper uptake in the cyanobacteriumNostoc calcicola Br�b
Biology of Metals (1991)
-
Pleiotropic mutations in appR reduce pH 2.5 acid phosphatase expression and restore succinate utilisation in CRP-deficient strains of Escherichia coli
Molecular and General Genetics MGG (1986)