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Distribution of Alkaline Phosphatase in the Arteries of Several Species

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Abstract

A CHANCE observation in our laboratory led us to study the activity of the alkaline non-specific monoesterase in the arterial wall. The distribution of this enzyme within the arteries has received but scant attention and contradictory reports appear in the literature. Kay1 states that none is found when chemical methods are used, whereas Gomori2, using a histochemical technique, reports that the enzyme is found in the adventitia of medium-sized arteries. In the human being, no activity has been found3 chemically in the aorta at an alkaline pH, or only traces found in this vessel and in other arteries4; on the other hand, the enzyme has been demonstrated histochemically in early atheromatous plaques5 as well as chemically in peripheral arteries6.

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References

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Author notes

  1. MARTHA A. FERNANDEZ and ALVARO L. GIMENO: Fellow of the Consejo Nacional de Investigaciones Cientfficas y Técnicas.

Authors and Affiliations

  1. Institute of Physiology, University of Buenos Aires Medical School,

    MANUEL RENÉ MALINOW, MARTHA A. FERNANDEZ, ALVARO L. GIMENO & GRATO E. BUR

Authors
  1. MANUEL RENÉ MALINOW
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  2. MARTHA A. FERNANDEZ
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  3. ALVARO L. GIMENO
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  4. GRATO E. BUR
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MALINOW, M., FERNANDEZ, M., GIMENO, A. et al. Distribution of Alkaline Phosphatase in the Arteries of Several Species. Nature 183, 1262–1263 (1959). https://doi.org/10.1038/1831262a0

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