Abstract
THE striking disappearance of erythroblasts from the bone marrow of bilaterally nephrectomized dogs, kept alive by peritoneal dialysis, has been reported1. Erythroblastopænia is likewise observed in patients with acute renal failure, but does not occur in cases of chronic uræmia, in spite of similar non-protein nitrogen blood-levels in the two situations. These observations suggest that the kidney produces a specific erythropoietic factor. The present study with iron-59 demonstrates the abolition of erythropoiesis following bilateral nephrectomy.
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References
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NAETS, J. Erythropoiesis in Nephrectomized Dogs. Nature 181, 1134–1135 (1958). https://doi.org/10.1038/1811134b0
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DOI: https://doi.org/10.1038/1811134b0
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