Abstract
THE well-known viscous nature of solutions of lysed cells of M. lysodeiklicus, attributed in part to nucleic acids, led to the search for an active nucleotide polymerase in this organism. Preliminary studies with 14C-labelled adenosine diphosphate (ADP) (the initial paper chromatographic studies were done in collaboration with Dr. Peter Olmsted) and the technique described by Grunberg-Manago and Ochoa1 revealed the presence of such an enzyme. The present communication deals with the enzymic synthesis and properties of the polymer (AMP)n.
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References
Grunberg-Manago, M., and Ochoa, S., J. Amer. Chem. Soc., 77, 3165 (1955).
Grunberg-Manago, M., Ortiz, P. J., and Ochoa, S., Science, 122, 907 (1955).
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BEERS, R. Enzymic Synthesis and Properties of a Polynucleotide from Adenosine Diphosphate. Nature 177, 790–791 (1956). https://doi.org/10.1038/177790a0
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DOI: https://doi.org/10.1038/177790a0
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