Abstract
APPLICATION of histochemical methods to electron microscopy is a logical development of biochemical and biophysical techniques. The comparatively limited resolution of the light microscope fails to reveal the relationship of normal cellular ultrastructure to the sites of histochemical reactions. Therefore, it seemed desirable to utilize recent developments in electron microscopy of biological material1 in the hope of learning more about the structures demonstrated with these techniques.
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BRANDES, D., ZETTERQVIST, H. & SHELDON, H. Histochemical Techniques for Electron Microscopy: Alkaline Phosphatase. Nature 177, 382–383 (1956). https://doi.org/10.1038/177382a0
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DOI: https://doi.org/10.1038/177382a0
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