Abstract
THE optimal bone graft is one which is most readily : (1) accepted with least reaction, (2) incorporated in callus formation, (3) vascularized with subsequent mineralization, and (4) absorbed (remodelled) by the host. Assuming that the constituents of bone which cause failure are contained in the organic fraction (antigens, fats, mucopolysaccharides, etc.), its removal would allow host acceptance of foreign bone. The remaining inorganic matrix might then be suitable for surgical prosthesis in situations where ‘banked’ bone is now required. The use of such inorganic bone transplants would, in addition, alleviate the present problems of procuring, storing and supplying whole bone.
Similar content being viewed by others
References
Williams, J. B., and Irvine, J. W., Science, 119, 771 (1954).
Orell, S., J. Bone and Joint Surg., 35, 873 (1937).
Neuman, W. F., and Mulryan, B. J., A.E.C.U., 132 (University of Rochester, 1949).
Peckham, S. C., and Losee, F. L., J. Dent. Res., 34, 719 (1955).
Singer, Leon, and Armstrong, W. D., J. Dent. Res., 34, 728 (1955).
Hendricks, S. B., and Hill, W. L., Nat. Acad. Science, 36, 731 (1950). 95–100 per cent ethylenediamine, Eastman.
Engstrom, A., Bellman, S., and Engfeldt, B., Brit. J. Rad., 28 517 (1955).
Robinson, R. A., J. Bone and Joint Surg., 34 A, 389 (1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LOSEE, F., HURLEY, L. Bone treated with Ethylenediamine as a Successful Foundation Material in Cross-Species Bone Grafts. Nature 177, 1032–1033 (1956). https://doi.org/10.1038/1771032a0
Issue Date:
DOI: https://doi.org/10.1038/1771032a0
- Springer Nature Limited
This article is cited by
-
Bridging large bone defects with a xenograft composited with autologous bone marrow
International Orthopaedics (1982)
-
Proteinmenge und Ossifikationstendenz verschiedener Knochen f�r Transplantationszwecke
Die Naturwissenschaften (1963)
-
Der transplantierte Knochenspan und seine Qualit�t nach partieller und vollst�ndiger Enteiwei�ung bei erhaltener anorganischer Substanz
Langenbecks Archiv f�r Klinische Chirurgie (1963)
-
Response of Oral Tissues to Grafts of Ethylenediamine-treated Heterogeneous Bone
Nature (1957)