Skip to main content
Log in

Diabetogenic Action of Pancreatic Glucagon

  • Letter
  • Published:

From Nature

View current issue Submit your manuscript

Abstract

IN previous experiments it has been shown that pancreatic glucagon, produced in the A cells of the pancreatic islets1, significantly increases the blood-sugar-level and the urine glucose of intact rats, forcibly fed on a high carbohydrate diet; in these conditions glucagon also augmented the diabetogenic effect of pituitary somatotropic and corticotropic hormones as well as of cortisone. Combined treatment with glucagon and cortisone was the most effective in provoking a temporary diabetic condition2.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Cavallero, C., Medicina (Parma), 2, 223 (1953).

    Google Scholar 

  2. Cavallero, C., and Malandra, B., Acta Endocrinol., 13, 79 (1953).

    Article  CAS  Google Scholar 

  3. Sutherland, E. W., Cori, C. F., Haynes, R., and Olsen, A. S., J. Biol. Chem., 180, 825 (1949).

    CAS  PubMed  Google Scholar 

  4. Gomori, G., Amer. J. Path., 15, 497 (1939).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CAVALLERO, C., MALANDRA, B. & GALANSINO, G. Diabetogenic Action of Pancreatic Glucagon. Nature 173, 585–586 (1954). https://doi.org/10.1038/173585b0

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/173585b0

  • Springer Nature Limited

This article is cited by

Navigation