Abstract
A detailed NMR description of the compact unfolded state of an unstable protein reveals the existence of native and non-native structure under non-denaturing conditions. The structural characterization of this and similar species may provide clues about protein folding mechanisms.
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Acknowledgements
The insights of O. Bilsel, C.R. Matthews, V. Smith, and J. Zitzewitz are gratefully acknowledged.
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Lecomte, J., Falzone, C. Where U and I meet. Nat Struct Mol Biol 6, 605–608 (1999). https://doi.org/10.1038/10643
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DOI: https://doi.org/10.1038/10643
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