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An Efficient One-Pot Synthesis of Triamides and Amidodiesters

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Abstract

An efficient one-pot procedure has been proposed for the synthesis of compounds containing three carboxamide groups or one carboxamide and two ester groups. The procedure is based on three-component condensation of alkyl isocyanides with 5-alkylidene- or 5-arylmethylene-substituted Meldrum's acids in the presence of such nucleophiles as phenols and amines.

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Authors
  1. A. Shaabani
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  2. M. B. Teimouri
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  3. H. R. Bijanzadeh
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Shaabani, A., Teimouri, M.B. & Bijanzadeh, H.R. An Efficient One-Pot Synthesis of Triamides and Amidodiesters. Russian Journal of Organic Chemistry 40, 976–981 (2004). https://doi.org/10.1023/B:RUJO.0000045188.81414.1d

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  • DOI: https://doi.org/10.1023/B:RUJO.0000045188.81414.1d

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