Skip to main content
SpringerLink
Log in

Synthesis of 5-Alkyl-1,3-bis[2-hydroxy-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)propyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-diones

  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

6-Methyluracil sodium salt reacts with 1,3-bis(3-chloro-2-hydroxypropyl)-6-methyluracils in DMF, yielding products of alkylation at the nitrogen atom in position 3 of the uracil ring.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. Reznik, V.S., Salikhov, I.Sh., Shvetsov, Yu.S., Shirshov, A.N., Bakulin, V.S., and Ivanov, B.E., Izv. Akad. Nauk SSSR, Ser. Khim., 1977, p. 880.

  2. Krivonogov, V.P., Tolstikov, G.A., Murinov, Yu.I., Zarudii, F.S., Lazareva, D.N., Ismagilova, A.F., Volkova, S.S., Sakhautdinova, G.M., Spirikhin, L.V., and Krivonogova, I.I., Khim.-Farm. Zh., 1993, vol. 27, p. 41.

    Google Scholar 

  3. Krivonogov, V.P., Tolstikov, G.A., Murinov, Yu.I., Zarudii, F.S., Lazareva, D.N., Ismagilova, A.F., Volkova, S.S., Sakhautdinova, G.M., Spirikhin, L.V., and Krivonogova, I.I., Khim.-Farm. Zh., 1996, vol. 30, p. 39.

    Google Scholar 

  4. Tolstikov, G.A., Krivonogov, V.P., Murinov, Yu.I., Galimov, B.I., Lazareva, D.N., Davydova, V.A., and Krivonogova, I.I., Khim.-Farm. Zh., 1995, vol. 29, p. 14.

    Google Scholar 

  5. Krivonogov, V.P., Tolstikov, G.A., Murinov, Yu.I., Zarudii, F.S., Lazareva, D.N., and Abdrakhmanov, I.B., Khim.-Farm. Zh., 1997, vol. 31, p. 24.

    Google Scholar 

  6. Krivonogov, V.P., Sivkova, G.A., Kozlova, G.G., Abdrakhmanov, I.B., Spirikhin, L.V., and Afzaletdinova, N.G., Russ. J. Org. Chem., 2002, vol. 38, p. 286.

    Google Scholar 

  7. Krivonogov, V.P., Sivkova, G.A., and Kozlova, G.G., Khim.-Farm. Zh., 2002, vol. 36, p. 8.

    Google Scholar 

  8. Khisamutdinov, R.A., Potapov, V.V., Murinov, Yu.I., and Krivonogov, V.P., Zh. Neorg. Khim., 2001, vol. 46, p. 517.

    Google Scholar 

  9. Khisamutdinov, R.A., Potapov, V.V., Murinov, Yu.I., and Krivonogov, V.P., Zh. Neorg. Khim., 2001, vol. 46, p. 513.

    Google Scholar 

  10. Shugar, D. and Fox, J., Biochim. Biophys. Acta, 1952, vol. 9, p. 199.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Organic Chemistry, Ufa Research Center, Russian Academy of Sciences, pr. Oktyabrya 71, Ufa, 450054, Bashkortostan, Russia

    V. P. Krivonogov, G. G. Kozlova, E. A. Belaya, G. A. Sivkova, L. V. Spirikhin, I. B. Abdrakhmanov & V. V. Plechev

Authors
  1. V. P. Krivonogov
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. G. Kozlova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. E. A. Belaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. A. Sivkova
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. L. V. Spirikhin
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. I. B. Abdrakhmanov
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. V. V. Plechev
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Krivonogov, V.P., Kozlova, G.G., Belaya, E.A. et al. Synthesis of 5-Alkyl-1,3-bis[2-hydroxy-3-(6-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)propyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-2,4-diones. Russian Journal of Organic Chemistry 40, 417–420 (2004). https://doi.org/10.1023/B:RUJO.0000034982.68023.eb

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:RUJO.0000034982.68023.eb

Keywords

Search

Navigation