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Synthesis of N-(3-Trimethylsilyl-2-propynoyl) Amino Acids

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Abstract

An efficient procedure has been developed for the preparation of previously unknown N-(3-trimethylsilyl-2-propynoyl) amino acids. The procedure is based on the reaction of 3-trimethylsilyl-2-propynoyl chloride with silylated amino acids which are generated in situ.

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Authors and Affiliations

  1. Favorskii Irkutsk Institute of Chemistry, Siberian Division, Russian Academy of Sciences, ul. Favorskogo 1, Irkutsk, 664033, Russia

    M. V. Andreev, A. S. Medvedeva, L. P. Safronova, A. V. Afonin & G. I. Sarapulova

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  1. M. V. Andreev
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  2. A. S. Medvedeva
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  3. L. P. Safronova
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  4. A. V. Afonin
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  5. G. I. Sarapulova
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Andreev, M.V., Medvedeva, A.S., Safronova, L.P. et al. Synthesis of N-(3-Trimethylsilyl-2-propynoyl) Amino Acids. Russian Journal of Organic Chemistry 39, 1706–1709 (2003). https://doi.org/10.1023/B:RUJO.0000019731.22994.0d

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  • DOI: https://doi.org/10.1023/B:RUJO.0000019731.22994.0d

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