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Tetrazoles: XLVI. 3H-1,3,4-Benzo- and Pyrido[6,7-b][1,3,4]triazepines from 5-Aryltetrazoles. Synthesis and Chemical Properties

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Abstract

2,5-Disubstituted 3H-1,3,4-benzotriazepines were synthesized by heating of N-imidoyltetrazoles in toluene at 110°C. Alkylation of these compounds, as well as of 3H-pyrido[6,7-b][1,3,4]triazepines with alkyl halides in THF in the presence of potassium tert-butoxide gave the corresponding 1-alkyl derivatives in good yield and with high regioselectivity.

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Authors and Affiliations

  1. St. Petersburg State Institute of Technology, Moskovskii pr. 26, St. Petersburg, 198013, Russia

    V. V. Nikulin, T. V. Artamonova & G. I. Koldobskii

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  1. V. V. Nikulin
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  2. T. V. Artamonova
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  3. G. I. Koldobskii
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Nikulin, V.V., Artamonova, T.V. & Koldobskii, G.I. Tetrazoles: XLVI. 3H-1,3,4-Benzo- and Pyrido[6,7-b][1,3,4]triazepines from 5-Aryltetrazoles. Synthesis and Chemical Properties. Russian Journal of Organic Chemistry 39, 1525–1529 (2003). https://doi.org/10.1023/B:RUJO.0000010575.49890.da

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  • DOI: https://doi.org/10.1023/B:RUJO.0000010575.49890.da

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