Skip to main content
SpringerLink
Log in

Synthesis of Methyl 5(6)-(4-Aminophenoxy)- and 5(6)-(2-Aminophenoxy)-2-benzimidazolyl Carbamates and Their Biological Properties

  • Published:
Russian Journal of Organic Chemistry Aims and scope Submit manuscript

Abstract

A procedure was developed for preparation of methyl 5(6)-(4-aminophenoxy)- and 5(6)-(2-aminophenoxy)-2-benzimidazolyl carbamates by reaction of 3,4,4`-triaminodiphenyl or 3,4,2`-triaminodiphenyl ethers respectively with methyl cyanocarbamate in water solution in the presence of 7-10 molar excess of acetic acid. The helminthicidal properties, embryotoxicity, and overall toxicity of compounds obtained were estimated.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

REFERENCES

  1. German Patent 2348104, 1973; Ref. Zh. Khim., 1975, 24 O 112.

  2. Kosareva, V.M., Solonenko, I.G., Mikhailyuk, A.N., Sorokina, O.N., Demidov, N.V., and Volkova, G.N., USSR Inventor,s Certificate 1140433, 1983; Byull. Izobr., 1985, no. 6.

  3. Japan Patent 47-33333, 1972; Ref. Zh. Khim., 1973, 11N146.

  4. Pilyugin, V.C., Valitov, R.B., Kuznetsova, C.L., Kiseleva, G.V., Klimakova, E.V., Vorob'eva, T.P., and Sapozhnikov, Yu.E., Bash. Khim. Zh., 2000, vol. 7, no. 4, p. 43.

    Google Scholar 

  5. Pilyugin, V.C., Kiseleva, G.V., Kuznetsova, C.L., and Chikisheva, G.E., Bash. Khim. Zh., 2001, vol. 8, no. 1, p. 11.

    Google Scholar 

  6. Abuzar, S., Rao, K.V.B., Sharma, S., Gupta, S., and Katiyar, J.C., Indian J. Chem., 1985, vol. 24, no. 2, p. 178.

    Google Scholar 

  7. German Patent 2425704, 1975; Ref. Zh. Khim., 1976

  8. German Patent 2425705, 1975; Ref. Zh. Khim., 1976, 17 O 134.

  9. Brewster, R.Q. and Roje, J.A., J. Am. Chem. Soc., 1939, vol. 61, p. 2416.

    Google Scholar 

  10. Coleman, G.H. and Talbot, W.F., Organic Syntheses, 1943; Translated under the Title Sintezy organicheskikh preparatov, Moscow: Inostr. Lit., 1949.

  11. Kornblum, N., Sintezy organicheskikh preparatov (Organic Synthesis), Moscow: Inostr. Lit., 1952, p. 203.

    Google Scholar 

  12. Sergent, A.A., Konstanty ionizatsii kislot i osnovanii (Ionization Constants of Acids and Bases), Moscow: Khimiya, 1964, p. 138.

    Google Scholar 

  13. UK Patent 1239104, 1971; Ref. Zh. Khim., 1972, 2 N 635.

Download references

Author information

Authors and Affiliations

  1. Research Technological Institute of Herbicides and Plant Growth Control Compounds, Academy of Sciences of Bashkortostan, Ufa, 450025, Russia

    V. S. Pilyugin, A. N. Mikhailyuk, V. M. Kosareva, G. E. Chikisheva, G. V. Kiseleva, S. L. Kuznetsova, T. P. Vorobyeva & E. V. Klimakova

Authors
  1. V. S. Pilyugin
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. A. N. Mikhailyuk
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. V. M. Kosareva
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. E. Chikisheva
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. V. Kiseleva
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. S. L. Kuznetsova
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. T. P. Vorobyeva
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. E. V. Klimakova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pilyugin, V.S., Mikhailyuk, A.N., Kosareva, V.M. et al. Synthesis of Methyl 5(6)-(4-Aminophenoxy)- and 5(6)-(2-Aminophenoxy)-2-benzimidazolyl Carbamates and Their Biological Properties. Russian Journal of Organic Chemistry 39, 1154–1160 (2003). https://doi.org/10.1023/B:RUJO.0000010185.19571.76

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:RUJO.0000010185.19571.76

Keywords

Search

Navigation