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Survival ofDrosophila melanogaster Progeny after Prolonged Suppression of Pairing and Recombination in Autosome 3

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Abstract

Two laboratory strains of Drosophila melanogaster carrying autosome 3 with a meiotic mutation c(3)G, that is maintained since 1985 in various balancer chromosomes, were used to study progeny survival. The conditions of maintenance of these strains and the effect of c(3)G mutation completely suppress pairing and crossing over in autosome 3. In addition, selection pressure was reduced because of permanent heterozygosity, mediating mutation accumulation in the studied chromosome. In both strains, all homozygotes for autosome 3 (c(3)G/c(3)G) perished. The hybrid homozygotes carrying chromosomes with c(3)G mutation from different strains survived in 0.4 of the progeny. Higher viability was observed after normal pairing and meiotic recombination of the studied chromosome with the chromosome from the wild-type line. The possible nature of mutations accumulated after prolonged suppression of chromosome pairing and recombination is discussed.

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  1. Vavilov Institute of General Genetics, Russian Academy of Sciences, Moscow, 119991, Russia

    V. L. Chubykin

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Chubykin, V.L. Survival ofDrosophila melanogaster Progeny after Prolonged Suppression of Pairing and Recombination in Autosome 3. Russian Journal of Genetics 40, 1223–1228 (2004). https://doi.org/10.1023/B:RUGE.0000048664.37169.ec

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