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Derivatives of Methyl N-[5(6)-(4-Aminophenylsulfanyl)benzimidazol-2-yl]carbamate and Phthalic Anhydrides. Synthesis and Biological Properties

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Abstract

Products of the reactions methyl N-[5(6)-(4-aminophenylsulfanyl)benzimidazol-2-yl]carbamate with phthalic anhydrides, involving the aniline nitrogen atoms, were obtained. Biological properties (embryotoxicity and toxicity) of the products and their mixtures with phase-transfer catalysts were studied. On this basis, new antihelminthic agents were developed.

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Authors and Affiliations

  1. Research Technological Institute of Herbicides and Growth Regulators, Academy of Sciences of Bashkortostan, Ufa, Bashkortostan, Russia

    V. S. Pilyugin, A. N. Mikhailyuk, V. M. Kosareva, G. E. Chikireva, G. V. Kiseleva & S. L. Kuznetsova

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  1. V. S. Pilyugin
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  2. A. N. Mikhailyuk
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  3. V. M. Kosareva
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  4. G. E. Chikireva
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  5. G. V. Kiseleva
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  6. S. L. Kuznetsova
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Pilyugin, V.S., Mikhailyuk, A.N., Kosareva, V.M. et al. Derivatives of Methyl N-[5(6)-(4-Aminophenylsulfanyl)benzimidazol-2-yl]carbamate and Phthalic Anhydrides. Synthesis and Biological Properties. Russian Journal of General Chemistry 74, 393–398 (2004). https://doi.org/10.1023/B:RUGC.0000030396.95958.31

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  • DOI: https://doi.org/10.1023/B:RUGC.0000030396.95958.31

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