Abstract
A series of new α-substituted acrolein dimethylhydrazones containing an acetal group were synthesized. These hydrazones react with acrylonitrile or methyl acrylate according to the Diels—Alder reaction pattern to give substituted tetrahydropyridines. An unusual [2+4]- and [2+3]-cycloaddition cascade reaction involving α-diethoxymethylacrolein dimethylhydrazone was discovered.
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Vahmistrov, V.E., Tsvetkov, N.P., Koldobsky, A.B. et al. Synthesis and cycloaddition reactions of α-substituted acrolein dimethylhydrazones containing an acetal group. Russian Chemical Bulletin 53, 233–235 (2004). https://doi.org/10.1023/B:RUCB.0000024854.07835.fc
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DOI: https://doi.org/10.1023/B:RUCB.0000024854.07835.fc