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Crystal Structure of the Azoxy Compound Formed by Photochemical Transformation of Niphedipine

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Abstract

The crystal structure of 2,2'-bis[2,6-dimethyl-3,5-di(methoxycarbonyl)pyridinyl-4]azoxybenzene has been determined; the compound is formed as the major product of photodegradation of niphedipine subjected to prolonged exposure of its ethanolic solution to daylight and artificial illumination. It is established that in crystal, the above azoxy derivative has a trans configuration.

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REFERENCES

  1. S. Goldmann and J. Stoltefuss, Angew. Chem. Int. Ed., 30, 1559-1578 (1991).

    Google Scholar 

  2. É. Lukevitz, Khim. Geterotsikl. Soedin., No. 6, 723-734 (1995).

    Google Scholar 

  3. M. A. Dumpis and N. I. Kudryashova, Khim.-Farm. Zh., 17, 1159-1169 (1983).

    Google Scholar 

  4. K. Görlitzer and D. Buss, Archiv Pharm., 314, 938-948 (1981).

    Google Scholar 

  5. H. De Vries and G. M. J. Beijersbergen van Henegouwen, Photochem. Photobiol., 62, 959-963 (1995).

    Google Scholar 

  6. Y. Matsuda, R. Teraoka, and I. Sugimoto, Int. J. Pharm., 54, 211-221 (1989); Chem. Abstr. 83 532-538 (1989).

    Google Scholar 

  7. N. Hayase, Yu.-I. Itagaki, S. Ogawa, et al., J. Pharm. Sci., 83, 532-538 (1994).

    Google Scholar 

  8. V. F. Sedova, T. V. Voevoda, T. G. Tolstikova, and O. P. Shkurko, Khim-Farm. Zh., No. 6, 4-7 (2002).

    Google Scholar 

  9. F. H. Allen and O. Kennard, Chem. Des. Autom. News, 8, 31-37 (1993).

    Google Scholar 

  10. A. Domanski, K. Ejsmout, J. B. Kyziol, and J. Zaleski, Acta Crystallogr., Sec. C, 57, 467-470 (2001).

    Google Scholar 

  11. K. Ejsmout, A. Domanski, J. B. Kyziol, and J. Zaleski, ibid., 56, 697-699 (2000).

    Google Scholar 

  12. E. Buncel, S. R. Keum, M. Cygler, et al., Can. J. Chem., 62, 1628-1639 (1984).

    Google Scholar 

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Authors and Affiliations

  1. N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch, Russian Academy of Sciences, Russia

    T. V. Rybalova, V. F. Sedova, Yu. V. Gatilov & O. P. Shkurko

Authors
  1. T. V. Rybalova
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  2. V. F. Sedova
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  3. Yu. V. Gatilov
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  4. O. P. Shkurko
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Rybalova, T.V., Sedova, V.F., Gatilov, Y.V. et al. Crystal Structure of the Azoxy Compound Formed by Photochemical Transformation of Niphedipine. Journal of Structural Chemistry 44, 870–873 (2003). https://doi.org/10.1023/B:JORY.0000029827.73545.3e

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  • DOI: https://doi.org/10.1023/B:JORY.0000029827.73545.3e

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