Abstract
Purpose : To evaluate leptin levels in a sample of obese women with PCOS and compare the results with obese and non-obese control, to be ultimately correlated with BMI, and insulin sensitivity.
Methods : Leptin and insulin assays by immuno-radiometric method, glucose assay by enzymatic colorimetric method.
Results : Leptin levels were significantly different between obese and non-obese subjects, and were significantly different between insulin resistant and non-insulin resistant obese PCOS, but were not significantly different between obese non-insulin resistant PCOS, and obese controls.
Conclusions : Body mass index and insulin resistance are the two main factors governing serum leptin levels.
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Saleh, H.A., El-Nwaem, M.A., El-Bordiny, M.M. et al. Serum Leptin Elevation in Obese Women with PCOS: A Continuing Controversy. J Assist Reprod Genet 21, 361–366 (2004). https://doi.org/10.1023/B:JARG.0000046204.81682.67
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DOI: https://doi.org/10.1023/B:JARG.0000046204.81682.67