Abstract
Procedures for determining lipoic acid by voltammetry and coulometric titration with electrogenerated halogens using the biamperometric indication of the titration end-point were developed. Possible mechanisms of lipoic acid oxidation with electrogenerated halogens are discussed. Microgram amounts of lipoic acid were determined in model solutions with an RSD of 1–2%. The analytical range of lipoic acid found by voltammetry at a glassy-carbon electrode lies between 1.15 × 10–5 and 1.73 × 10–4 M. The detection limit for lipoic acid is 5.75 × 10–6 M.
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Ziyatdinova, G.K., Budnikov, G.K. & Pogorel'tsev, V.I. Electrochemical Determination of Lipoic Acid. Journal of Analytical Chemistry 59, 288–290 (2004). https://doi.org/10.1023/B:JANC.0000018975.54696.2e
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DOI: https://doi.org/10.1023/B:JANC.0000018975.54696.2e