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Synthesis of Substituted 1,2,4-Triazoles and 1,3,4-Thiadiazoles

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

The cyclization of 4-substituted 1-arylacetyl- and 1-aryloxyacetylthiosemicarbazides and also the potassium salt of (4-bromophenoxy)acetodithiocarbazinic acid in the presence of base gives the novel 3-arylmethyl- and 3-aryloxymethyl-5-mercapto-1,2,4-triazoles and, in the presence of concentrated H2SO4, the novel 5-substituted 2-arylmethyl- and 2-aryloxymethyl-1,3,4-thiadiazoles.

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Authors and Affiliations

  1. A. L. Mndzhoyan Institute of Fine Organic Chemistry, Armenian Republic National Academy of Sciences, Yerevan, 375014

    T. R. Hovsepian, E. R. Dilanian, A. P. Engoyan & R. G. Melik-Ohanjanian

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  1. T. R. Hovsepian
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  2. E. R. Dilanian
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  3. A. P. Engoyan
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  4. R. G. Melik-Ohanjanian
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Hovsepian, T.R., Dilanian, E.R., Engoyan, A.P. et al. Synthesis of Substituted 1,2,4-Triazoles and 1,3,4-Thiadiazoles. Chemistry of Heterocyclic Compounds 40, 1194–1198 (2004). https://doi.org/10.1023/B:COHC.0000048294.27172.a3

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  • DOI: https://doi.org/10.1023/B:COHC.0000048294.27172.a3

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