Abstract
We have carried out solvolysis of the previously described ethyl esters of 3-methyl(aryl)-4-methyl-2-thioxothiazoline-5-carboxylic acids, leading to the corresponding acids without breaking down the heterocycle. We synthesized a series of novel esters from the latter by treatment with dimethyl sulfate or reactive halides. Of these, only in the case of the ethyl ester of 3,4-dimethyl-2-thioxothiazoline-5-carboxylic acid did we obtain the hydrazinolysis product (the hydrazide), from which we synthesized novel hydrazones by treatment with aldehydes and ketones.
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REFERENCES
N. N. Mel'nikov, K. P. Novozhilov, and T. N. Pylova, Chemicals for Plant Protection [in Russian], Khimiya, Moscow (1980), p. 263.
M. D. Mashkovskii, Drugs [in Russian], Meditsina, Moscow (1984), Pt. 1, p. 202.
V. V. Dovlatyan, K. A. Eliazyan, V. A. Pivazyan, E. A. Kazaryan, A. P. Engoyan, R. T. Grigoryan, and R. G. Mirzoyan, Khim. Geterotsikl. Soedin., 677 (2000).
V. A. Mamedov, N. A. Nuretdinov, and F. G. Sigbatulina, Izv. Akad. Nauk SSSR. Ser. Khim., 2835 (1991).
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Dovlatyan, V.V., Eliazyan, K.A., Pivazyan, V.A. et al. Some Conversions of Thiazoline Carboxylic Acid Esters. Chemistry of Heterocyclic Compounds 39, 1238–1241 (2003). https://doi.org/10.1023/B:COHC.0000008273.38554.9a
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DOI: https://doi.org/10.1023/B:COHC.0000008273.38554.9a