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Some Conversions of Thiazoline Carboxylic Acid Esters

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

We have carried out solvolysis of the previously described ethyl esters of 3-methyl(aryl)-4-methyl-2-thioxothiazoline-5-carboxylic acids, leading to the corresponding acids without breaking down the heterocycle. We synthesized a series of novel esters from the latter by treatment with dimethyl sulfate or reactive halides. Of these, only in the case of the ethyl ester of 3,4-dimethyl-2-thioxothiazoline-5-carboxylic acid did we obtain the hydrazinolysis product (the hydrazide), from which we synthesized novel hydrazones by treatment with aldehydes and ketones.

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Dovlatyan, V.V., Eliazyan, K.A., Pivazyan, V.A. et al. Some Conversions of Thiazoline Carboxylic Acid Esters. Chemistry of Heterocyclic Compounds 39, 1238–1241 (2003). https://doi.org/10.1023/B:COHC.0000008273.38554.9a

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  • DOI: https://doi.org/10.1023/B:COHC.0000008273.38554.9a

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