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Effects of Pineal Peptides on Circadian Dynamics of Spermatogonia Proliferation in Albino Rats

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Abstract

Mitotic index of type B spermatogonia in intact animals is characterized by a circadian rhythm. Mitotic index increased and its circadian rhythm disappeared after pinealectomy. Treatment with Epithalamin for 14 days restored the circadian rhythm. The circadian biorhythm of spermatogonia proliferation suggests the presence of circadian rhythm of spermatogenesis in general and its regulation by the pineal gland.

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Arav, V.I., Sych, V.F., Zheleznyak, E.V. et al. Effects of Pineal Peptides on Circadian Dynamics of Spermatogonia Proliferation in Albino Rats. Bulletin of Experimental Biology and Medicine 137, 597–600 (2004). https://doi.org/10.1023/B:BEBM.0000042722.66262.de

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  • DOI: https://doi.org/10.1023/B:BEBM.0000042722.66262.de

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