Skip to main content
Log in

Blebbing of Thymocyte Plasma Membrane and Apoptosis are Related to Impairment of Capacitance Ca2+ Entry into Cells

  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

We studied the role of disturbances in cell Ca2+ homeostasis in plasma membrane blebbing and death of thymocytes. Capacitance Ca2+ channels of the plasma membrane and intracellular Ca2+ stores are involved in the induction and progression of changes in the membrane and cytoskeleton and apoptosis induced by acrylonitrile.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

REFERENCES

  1. L. I. Andreeva, L. A. Kozhemyakin, and A. A. Kishkun, Lab. Delo, No. 11, 41-43 (1988).

  2. Y. Ando, M. Kuroda, O. Honda, et al., Int. J. Mol. Med., 7, 243-247 (2001).

    PubMed  Google Scholar 

  3. M. D. Cahalan, H. Wulff, and K. G. Chandy, J. Clin. Immunol., 21, No. 4, 235-252 (2001).

    PubMed  Google Scholar 

  4. R. G. Deschesnes, J. Huot, K. Valerie, and J. Landry, Mol. Biol. Cell, 12, 1569-1582 (2001).

    PubMed  Google Scholar 

  5. J. Hagmann, M. M. Burger, and D. Dagan, J. Cell Biochem., 73, 488-499 (1999).

    PubMed  Google Scholar 

  6. A. M. Hurne, C. L. L. Chai, K. Moerman, and P. Waring, J. Biol. Chem., 277, No. 35, 31, 631-31, 638 (2002).

    Google Scholar 

  7. J. Jiang, H. Zhang, J. E. Trosko, et al., Cell Biol. Toxicol., 15, No. 3, 173-183 (1999).

    PubMed  Google Scholar 

  8. J. A. Joseph, J. G. Strain, N. D. Jimenez, and D. Fisher, J. Neurochem., 69, 1252-1258 (1997).

    PubMed  Google Scholar 

  9. R. S. Lewis, Annu. Rev. Immunol., 19, 497-521 (2001).

    PubMed  Google Scholar 

  10. M. C. Martinez and J.-M. Freyssinet, BMC Cell Biol., 2, No. 1, 20 (2001).

    PubMed  Google Scholar 

  11. R. P. Mason, I. T. Mak, M. W. Trumbore, and P. E. Mason, Am. J. Cardiol., 84, No. 4A, 16L-22L (1999).

    PubMed  Google Scholar 

  12. S. Orrenius, D. J. McConkey, G. Bellomo, and P. Nicotera, TIPS, 10, 281-285 (1989).

    PubMed  Google Scholar 

  13. H. L. Pahl, Phys. Rev., 79, No. 3, 683-701 (1999).

    Google Scholar 

  14. J. W. Jr. Putney and C. M. P. Ribeiro, Cell Mol. Life Sci., 57, 1272-1286 (2000).

    PubMed  Google Scholar 

  15. C. Richter and J. Schlegel, Toxicol. Lett., 67, 119-127 (1993).

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mikhutkina, S.V., Salmina, A.B., Sychev, A.V. et al. Blebbing of Thymocyte Plasma Membrane and Apoptosis are Related to Impairment of Capacitance Ca2+ Entry into Cells. Bulletin of Experimental Biology and Medicine 137, 551–555 (2004). https://doi.org/10.1023/B:BEBM.0000042709.57599.67

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1023/B:BEBM.0000042709.57599.67

Navigation