Abstract
We studied the role of disturbances in cell Ca2+ homeostasis in plasma membrane blebbing and death of thymocytes. Capacitance Ca2+ channels of the plasma membrane and intracellular Ca2+ stores are involved in the induction and progression of changes in the membrane and cytoskeleton and apoptosis induced by acrylonitrile.
Similar content being viewed by others
REFERENCES
L. I. Andreeva, L. A. Kozhemyakin, and A. A. Kishkun, Lab. Delo, No. 11, 41-43 (1988).
Y. Ando, M. Kuroda, O. Honda, et al., Int. J. Mol. Med., 7, 243-247 (2001).
M. D. Cahalan, H. Wulff, and K. G. Chandy, J. Clin. Immunol., 21, No. 4, 235-252 (2001).
R. G. Deschesnes, J. Huot, K. Valerie, and J. Landry, Mol. Biol. Cell, 12, 1569-1582 (2001).
J. Hagmann, M. M. Burger, and D. Dagan, J. Cell Biochem., 73, 488-499 (1999).
A. M. Hurne, C. L. L. Chai, K. Moerman, and P. Waring, J. Biol. Chem., 277, No. 35, 31, 631-31, 638 (2002).
J. Jiang, H. Zhang, J. E. Trosko, et al., Cell Biol. Toxicol., 15, No. 3, 173-183 (1999).
J. A. Joseph, J. G. Strain, N. D. Jimenez, and D. Fisher, J. Neurochem., 69, 1252-1258 (1997).
R. S. Lewis, Annu. Rev. Immunol., 19, 497-521 (2001).
M. C. Martinez and J.-M. Freyssinet, BMC Cell Biol., 2, No. 1, 20 (2001).
R. P. Mason, I. T. Mak, M. W. Trumbore, and P. E. Mason, Am. J. Cardiol., 84, No. 4A, 16L-22L (1999).
S. Orrenius, D. J. McConkey, G. Bellomo, and P. Nicotera, TIPS, 10, 281-285 (1989).
H. L. Pahl, Phys. Rev., 79, No. 3, 683-701 (1999).
J. W. Jr. Putney and C. M. P. Ribeiro, Cell Mol. Life Sci., 57, 1272-1286 (2000).
C. Richter and J. Schlegel, Toxicol. Lett., 67, 119-127 (1993).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Mikhutkina, S.V., Salmina, A.B., Sychev, A.V. et al. Blebbing of Thymocyte Plasma Membrane and Apoptosis are Related to Impairment of Capacitance Ca2+ Entry into Cells. Bulletin of Experimental Biology and Medicine 137, 551–555 (2004). https://doi.org/10.1023/B:BEBM.0000042709.57599.67
Issue Date:
DOI: https://doi.org/10.1023/B:BEBM.0000042709.57599.67