Abstract
Esters of (arylhydrazono)chloroacetic acid reacted with tris(hydroxymethyl)aminomethane in the presence of trimethylamine under mild conditions to give 3-(arylhydrazonoyl)-5,5-di(hydroxymethyl)-2-oxomorpholines.
Similar content being viewed by others
REFERENCES
N. A. Terent'eva, M. L. Petrov, K. A. Potekhin, Yu. T. Struchkov, and V. A. Galishev, Zh. Org. Khim., 30, 344 (1994).
M. Abramov and M. L. Petrov, Zh. Obshch. Khim., 65, 308 (1995).
A. O. Abdelhamid, H. F. Zohdi, and N. M. Rateb, J. Chem. Res. (S), 4, 144 (1995); Chem. Abstr., 123, 32002 (1995).
A. K. Mansour, N. M. Elwan, H. A. Abdelhadi, T. A. Abdallah, and H. M. Hassaneen, Sulfur. Lett., 18, 105 (1995); Chem. Abstr., 124, 317107 (1996).
H. A. Albar, J. Chem. Res. (S), 7, 316 (1996); Chem. Abstr., 125, 275047 (1996).
R. Fusco and G. Bianchetti, Gazz. Chim. Ital., 87, 438 (1957).
M. O. Lozinskii, V. N. Bondar, S. V. Konovalikhin, O. A. D'yachenko, and L. O. Atovmyan, Izv. Akad. Nauk SSSR, Ser. Khim., 2635 (1990).
Yu. P. Kitaev and B. I. Buzykin, Hydrazones [in Russian], Nauka, Moscow (1974), 56.
Yu. A. Sokolova, O. A. D'yachenko, L. O. Atovmyan, V. N. Bondar, and M. O. Lozinskii, Zh. Struktur. Khim., 30, 141 (1989).
M. O. Lozinskii, S. N. Kukota, and P. S. Pel'kis, Ukr. Khim. Zh., 33, 1295 (1967).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Bodnar, V.N., Britsun, V.N. & Lozinskii, M.O. Synthesis of 3-(Arylhydrazono)-5,5-di(hydroxymethyl)-2-oxomorpholines. Chemistry of Heterocyclic Compounds 39, 790–793 (2003). https://doi.org/10.1023/A:1025659515530
Issue Date:
DOI: https://doi.org/10.1023/A:1025659515530