Abstract
We studied the effects of Retinalamin (polypeptide preparation isolated from the retina) and a synthetic peptide Epithalon (Ala-Glu-Asp-Gly) on proliferative activity of retinal and pigmented epithelial cells. Experiments showed that Retinalamin and Epithalon (in certain concentrations) tissue-specifically stimulated proliferation of retinal and pigmented epithelial cell in culture.
Similar content being viewed by others
REFERENCES
N. Bakhvalov, N. Zhidkov, and G. Kobel'kov, Numerical Methods [in Russian], Moscow (2000).
V. Ya. Brodskii, V. Kh. Khavinson, Yu. A. Zolotarev, et al., Izvestiya Akad. Nauk. Ser. Biology, No. 5, 517-521 (2001).
G. V. Lopashov and V. N. Zemchikhina, Uspekhi Sovrem. Biol., 120,No. 6, 540-549 (2000).
G. P. Pinaev, Methods of Cell Culturing [in Russian], Leningrad (1988).
R. Freshney, Animal Cell Cultures [in Russian], Moscow (1989).
V. Kh. Khavinson, Byull. Eksp. Biol. Med., 132,No. 8, 228-229 (2001).
V. Kh. Khavinson, V. V. Malinin, N. I. Chalisova, and E. I. Grigor'ev, Uspekhi Gerontol., No. 9, 95-100 (2002).
V. Kh. Khavinson, V. V. Malinin, S. V. Trofimova, and V. N. Zemchikhina, Byull. Eksp. Biol. Med., 134,No. 11, 560-563 (2002).
M. Asashima, H. Nakano, and K. Shimada, Roux Arch. Devel. Biol., 198, 330-335 (1990).
O. Yu. Chertov, A. L. Krasnosekskii, M. E. Bogdanov, and O. A. Hoperskaya, Biomed. Sci., 1,No. 5, 499-506 (1990).
V. Khavinson, Neuroendocrinol. Lett. 23,Suppl. 3, 11-144 (2002).
V. Khavinson, M. Razumovsky, S. Trofimova, et al., Ibid., 23,No. 4, 365-368 (2002).
G. V. Lopashov, O. N. Golubeva, and K. G. Zviadadze, Differentiation, 61, 237-242 (1997).
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Khavinson, V.K., Zemchikhina, V.N., Trofimova, S.V. et al. Effects of Peptides on Proliferative Activity of Retinal and Pigmented Epithelial Cells. Bulletin of Experimental Biology and Medicine 135, 597–599 (2003). https://doi.org/10.1023/A:1025497806636
Issue Date:
DOI: https://doi.org/10.1023/A:1025497806636